KIT and posterior cortical atrophy: We posit that the stimulation of the migratory and invasive abilities induced by c-KIT in these PCa cells would be mediated by an EMT-like phenomenon, as we observed a change in morphology toward a more mesenchymal phenotype, an increase in expression of Snail1, Slug, Zeb1, and vimentin, and a decrease in E-cadherin expression in c-kit-transfected PCa cell lines as compared to the same PCa cells transfected with the empty vector (EV) (c-kit-negative control cells) (Figure 5).