The sequencing data showed that both the PD patients and the controls harbor five single nucleotide polymorphism mutations of OTUD3 (rs75742716 T > G, c.1008C > A, rs2298110 A > G, rs10916668 A > G and rs78466831 A > G) (Fig. 6a–d), indicating that OTUD3 N321S, A333T, and G288D mutant proteins might be expressed. This evidence concerns the gene OTUD3 and Parkinson disease.