KAT2A and cardiac hypertrophy: As cardiomyocyte apoptosis is associated with the development of cardiac hypertrophy [23], we examined whether GCN5 impacts cardiomyocyte apoptosis during this process; levels of several apoptosis-associated proteins were quantified, and GCN5 overexpression significantly promoted apoptosis, as evidenced by increased pro-apoptotic protein levels and downregulated anti-apoptotic protein expression.