Among them, only 16 genes (down-regulated: PDPN, TUBA1C, LGALS3, FABP5, ANXA2P1, ANXA2, C1RL, KCNE4, LGALS1, DCDC2, MIR155HG, CSTA, BCL3 and FBXO17; up-regulated: RANBP17 and DLL1) were dysregulated in IDH1mut GBM simultaneously (Figure 3E and Supplementary Figure 1). The gene discussed is ANXA2; the disease is glioblastoma.