Similarly, FGFR1 silencing affected NB cell ability to migrate through a matrigel-coated membrane (Fig. 2C and Additional file 1: Fig. S2A) and the anchorage-independent growth, as shown by soft agar assay (Fig. 2D and Additional file 1: Fig. S2B). The gene discussed is FGFR1; the disease is neuroblastoma.