HOXC6 and central nervous system cancer: The HOXC6-bound DNA motifs were identified by using MEME software (Fig. 5A), and the distribution of HOXC6 peak binding locations across the genome is shown in Fig. 5B. To further clarify the biological roles of HOXC6 expression in glioma, we selected 5225 genes from the TCGA dataset (Spearman’s R > 0.3, p < 0.05), 4064 genes from the CGGA dataset (Spearman’s R > 0.3, p < 0.05) and 3330 target genes from ChIP-seq (Fig. 5C).