HOXC6 and colon adenocarcinoma: As shown in Fig. 1C, HOXC6 was considered a risk factor for Glioblastoma multiforme (GBM), Brain Lower Grade Glioma (LGG), Adrenal Cortical Carcinoma (ACC), Colon Adenocarcinoma (COAD), Head and Neck Squamous Cell Carcinoma (HNSC), Liver Hepatocellular Carcinoma (LIHC) and Lung Adenocarcinoma (LUAD) with p values of less than 0.05.