ERBB2 and neoplasm: The efficiency of combination therapy was further strengthened by the previous research findings that showed the capacity of TEA-VV to proliferate in HER2- redirected CAR T-cells, indicating that CAR might be employed as a safe delivery vehicle for TEA-VV, protecting it from host exclusion [174] This unique technique might be used to treat tumor stroma and any other situation where specific T cell immune responses are restricted owing to immunosuppressive circumstances or physical limitations.