Doxorubicin induced significant tumor shrinkage in mice bearing OCI-Ly8 vector compared with those bearing OCI-Ly3 vector (p < 0.01), and the efficacy of doxorubicin on OCI-Ly8 was significantly reduced by ectopic expression of miRNA-363-3p (Fig. 1E, F; Supplementary Fig. 5C, D). Here, CD8B is linked to neoplasm.