MLH1 and polyposis: In colon adenomatous polyp formation oncogenes such as K-RAS (Kirsten Rat Sarcoma Virus) and MYC as well as tumor suppressors such as APC (Adenomatous Polyposis Coli) and p53 are more common whereas sessile tumors present mutations in DNA repair genes MLH1 (MutL homolog 1) and MLH2 (MutL homolog 2) [5,6].