The significant KEGG pathways are hematopoietic cell lineage (CD14, MS4A1, CD37, HLA-DPA1, HLA-DQB1), inflammatory bowel disease (TLR4, HLA-DPA1, HLA-DQB1), intestinal immune network for IgA production (HLA-DPA1, HLA-DQB1), JAK-STAT signaling pathway (CSF2RB, IL10RA), toll-like receptor signaling pathway (TLR4, CD14). The gene discussed is MS4A1; the disease is inflammatory bowel disease.