Furthermore, Enrichr and GSEA gene ontology analysis revealed that the transcriptional changes induced by IVIg in CD14+ monocytes greatly resemble the transcriptional changes that take place in monocytes in breast cancer patients (GSE65517) [45], and in PBMCs from heart failure (GSE9128) [46] and hepatocellular carcinoma [47] patients (GSE49515) (Fig. 1G). The gene discussed is CD14; the disease is breast cancer.