Genetic factors such as the patatin-like phospholipase domain containing 3 (PNPLA3), the transmembrane 6 superfamily member 2 (TM6SF2), the membrane-bound O-acyltransferase domain containing 7 (MBOAT7), and the glucokinase regulator (GCKR) [11] were also associated with the risk of NAFLD. The gene discussed is PNPLA3; the disease is metabolic dysfunction-associated steatotic liver disease.