For genes variable in liver, we found enrichment for TFs involved in diseases such as cancer (e.g. Evi1, Z-score = 9.9) and diabetes (e.g. Foxa2, Z-score = 8.5) (Wolfrum et al. 2004; Lugthart et al. 2008; Goyama and Kurokawa 2009). This evidence concerns the gene FOXA2 and diabetes mellitus.