LINC01606 promoted SCD1 expression by interacting with miR‐423‐5p and subsequently activated Wnt/β‐catenin signalling by controlling the synthesis of intracellular MUFAs, whereas activation of Wnt/β‐catenin signalling enhanced LINC01606 expression by TF TFE3, which could continuously increase the synthesis of MUFAs and neutralise the increase in lipid ROS under oxidative stress caused by ferroptosis inducers, which are necessary to maintain the stemness and ferroptosis resistance of cancer cells (Figure 12). Here, LINC01606 is linked to cancer.