TLR4 and childhood gender nonconformity: Our previous study demonstrated that deletion of myeloid‐TLR4 markedly alleviated progressive cGN and largely improved renal function by suppressing macrophage and neutrophil infiltration, and promoting macrophage polarization into the anti‐inflammatory M2 phenotype.[11] However, transcriptional regulation through which deletion of myeloid TLR4 leads to the shift of macrophages from the M1 to M2 phenotype in anti‐GBM cGN remains to be elucidated.