TLR4 and crescentic glomerulonephritis: To uncover the hypothetical TLR4‐dependent regulation on macrophage/monocytes differentiation in crescentic glomerulonephritis, we re‐clustered these populations (Cluster 0, 1, 3, 4, 7, 8, and 9) to construct single cell–based differentiation trajectory in our scRNA‐seq data (Figure 3A).