Regardless of clusters, deletion of myeloid‐TLR4 significantly suppressed pro‐inflammatory cytokine signaling, such as NF‐κB, IL‐17, and TNF signaling pathways, weakened the antigen presenting capacity, and gravely enhanced anti‐inflammatory signaling, including wound healing and TGFβ signaling within overall renal macrophages/monocytes at day 7 post anti‐GBM cGN (Figure 2E,F). The gene discussed is TGFB1; the disease is glioblastoma.