Despite a generally higher expression of FGF1 and FGF2 as compared to FGF19, the FGFR4high GBM subgroup expressed reduced FGF1 and FGF2, but enhanced FGF19 levels (p = E-9) (Fig. 2A, Additional File 1: Figure S4A). This evidence concerns the gene FGF2 and glioblastoma.