RASGRF1, CTSH and two additional genes that were strongly associated with BPD, NCOR2 (encoding nuclear receptor corepressor 2; cg24847366) and SPOCK2 (encoding SPARC (osteonectin), Cwcv, and Kazal-like domains proteoglycan 2; cg17958658), have previously been reported to be related to BPD pathogenesis or preterm GA [13, 18, 26, 27, 33, 42]. This evidence concerns the gene CTSH and bronchopulmonary dysplasia.