On the other hand, organoid cells of patient #7 were initially cultured in a chemical-defined medium, and both tumor cells and normal epithelial cells showed similar expression levels of OLFM4 and CA2. After the organoid cells were transferred into conditioned medium, this expression pattern of OLFM4 and CA2 was still maintained (Fig. 5B). This evidence concerns the gene OLFM4 and neoplasm.