Significant relative differences (p < 0.002) were also observed between dogs with DCM and healthy controls for the clinical biochemistry parameters total protein, globulin, ALT, ALP, blood urea nitrogen (BUN), creatinine and inorganic P. Compared to matched controls, ALT, ALP, BUN and inorganic P were often increased. Here, GPT is linked to familial dilated cardiomyopathy.