In addition, genes involved in Gln (that is, SLC38A5, SLC1A5), methionine (that is, SLC7A5) and iron uptake (TFRC) had higher expression in MYCN-amplified or MYCN-overexpressed neuroblastomas; TFRC was recently associated with ferroptosis in neuroblastomas12 (Fig. 6c,d and Extended Data Fig. 4c). Here, MYCN is linked to neuroblastoma.