Among the 10 enriched N-glycosylated proteins in the ALL-OA group compared to the NC group, the top three were cartilage intermediate layer protein 1 (CILP), immunoglobulin heavy constant mu (IGHM), and lumican (LUM), whereas the abundances of N-glycosylated fibrillin-1 (FBN1) and collagen type VI alpha 1 chain (COL6A1) were significantly decreased. The gene discussed is COL6A1; the disease is acute lymphoblastic leukemia.