SIRT1 and acute lymphoblastic leukemia: We did not detect an increase of SIRT1 mRNA in B/M MPAL and B-ALL cells as compared to normal B cells, and Sirt1 mRNA levels in B/M MPAL cells lied between that of normal B and myeloid cells, for which normal B cells had much higher Sirt1 mRNA than myeloid cells (Supplementary Fig. 3).