IFNA1 and infection: We hypothesized that type I and III IFN responses would be less vigorous to SARS-CoV-2 than to HRV infection, that IFN responses would be associated with SARS-CoV-2 replication, and that HRV pre-infection and/or recombinant IFN treatment of airway epithelial cultures would decrease replication of SARS-CoV-2. Some of the results of these studies have been previously reported in the form of an abstract26.