In addition, OVOL1 mRNA and protein levels were determined in commonly used breast cell lines with either epithelial and/or mesenchymal features, including normal breast epithelial cells MCF10A-M1, premalignant breast cells MCF10A-M2 and luminal breast cancer cells MCF7, and highly invasive mesenchymal breast cancer cell lines MDA-MB-436 and MDA-MB-231. The gene discussed is OVOL1; the disease is breast carcinoma.