OVOL1 and breast cancer: Despite a variety of evidence from experimental and mathematical modeling analyses characterize OVOL1 as an MET inducer in multiple cancers, the association between OVOL1 and EMP in breast cancer patient remains ill-defined.35,57–60 Through analyzing transcriptome datasets, a negative correlation between OVOL1 and EMT signature was uncovered in various patient cohorts (Fig. 1a).