Moreover, we found positive correlations between OVOL1 and epithelial markers (ECAD, EPCAM, and KRT18), and negative correlations between OVOL1 and mesenchymal markers (NCAD, VIM, and FN), in a breast cancer patient cohort and the aforementioned 51 cell line dataset (Supplementary Fig. 1b, c).37,39 E-cadherin and OVOL1 were more prominently expressed, while the mesenchymal markers, including N-cadherin, Vimentin, SNAIL, and SLUG, were lower expressed in ten luminal cell lines than ten basal cell lines (Fig. 1b). This evidence concerns the gene CDH2 and breast cancer.