CD123 expression levels were significantly higher in BPDCN (gated on CD45 + cells, mean fluorescence intensity [MFI] range 3,484–17,937) than in remission marrows (gated on CD34 + cells, MFI range 232–845; p ≤ 0.01) and in AML blasts (gated on CD45 + cells, MFI range 360–5073; p ≤ 0.01) (Supplementary Fig. 4). Here, CD34 is linked to acute myeloid leukemia.