METTL3 and hepatoblastoma: Interestingly, miRNAs also affect the expression of m6A-modified proteins, modulating the level of downstream target genes.173,174 For example, METTL3 is a direct target of miR-186 in hepatoblastoma (HB) cells.175 miR-4429 inhibits SEC62 stabilization caused by m6A by targeting METTL3 in GC to suppress GC cell proliferation.176 Yue et al.177 found that miR-96 downregulates AMPKα2, increasing FTO expression.