In fact, the role of various m6A reader proteins in cancer remains largely unexplored.119,242 Table 1 summarizes the role of m6A reader in cancer reported by some current studies.243–246 For example, Chen et al.209 found that IGF2BP2 enhanced the stabilianticodon stem-loopty of HMGA2, thereby promoting the metastasis of CRC cells and exerting a cancer-promoting effect. The gene discussed is IGF2BP2; the disease is cancer.