ITGB1 and Granuloma: The most abundant subcluster (8.3% of granuloma cells, q = 0.074, Dirichlet p = 0.00049; Figure 3D; Tables S3 and S4) exhibited elevated expression of markers of naive and memory T cells (TCF7, CCR7, IL7R, and TXNIP) and activation or memory state (CD69 and ITGB1) (Figure 3C; Table S4).