Regardless, reflecting on the physiological significance of Pso2, its human counterpart, SNM1A, is associated with cancer risk (Lee et al. 2016; Wang et al. 2016; Laporte et al. 2020); therefore, elucidation of the mechanism underlying the subcellular distribution of SNM1A would help in better understanding of its function in cancer susceptibility. The gene discussed is DCLRE1A; the disease is cancer.