A study by Esteghamati et al. showed that hypertensive patients without diabetes had significantly higher fasting plasma insulin levels (9.24 versus 7.86 mIU/L) and higher HOMA-IR (2.16 versus 1.75) when compared to normotensive non-diabetic patients.17 Akande et al. observed a 31% IR prevalence among hypertensive Nigerian patients, with a HOMA-IR cut-off value of >3.8 considered to be insulin-resistant.18 Although diabetics were excluded, these studies included obese individuals, which explains the higher HOMA-IR value when compared to our study. The gene discussed is INS; the disease is diabetes mellitus.