Likewise, a significant difference was observed in IL-21 levels in ME/CFS cases seropositive for virus dUTPases’ Abs compared with virus-seronegative cases (7818 ± 1481 versus 2672 ± 356.5, P = 0.0014) (Figure 1E). The gene discussed is IL21; the disease is myalgic encephalomeyelitis/chronic fatigue syndrome.