Microarray gene expression analysis of EBV dUTPase in human dendritic cells (hDCs) revealed a strong induction of inhibin subunit beta A (13), which encodes activin A. This finding along with the presence of heightened Ab levels against the dUTPase of multiple herpesviruses (8) suggest that EBV dUTPase might contribute to the immune dysfunction observed in ME/CFS through activin A, a potent inducer of TFH cell differentiation in humans (19). Here, INHBA is linked to myalgic encephalomeyelitis/chronic fatigue syndrome.