This authors also measured HGF levels in 6 patients with acute MI during the first day of ACS (repeated 10 times during the first day) and once at discharge from hospital; and found a marked increase in HGF levels in the first measurement, that were reduced to almost normal values within 5 h, with a second increase of HGF levels during the first 24 h in those patients who had serious cardiovascular events in the acute stage of MI (cardiac arrest and early re-occlusion of the coronary artery) [31]. This evidence concerns the gene HGF and myocardial infarction.