In contrast to the more established [68 Ga]Ga-PSMA-11, where prospective diagnostic accuracy studies have been performed [16], only limited data are available for [18F]PSMA-1007 with only preliminary observations in small cohorts [17], in mixed cohorts of primary and recurrent PC, [18] thereby with limited interpretability, or without any verification of positive findings [19, 20]. This evidence concerns the gene FOLH1 and pachyonychia congenita.