Circulating IL-10 concentrations were measured in 3 trials, of which 1 (33%) reported a significant increase following bLf 32.4 mg/d for 3 mo in adults with T2D (55), although there was no change following 1000 mg/d for 63 d in healthy females or infant formula with bLf ∼70 mg/d for 15 mo in young children (54). This evidence concerns the gene IL10 and type 2 diabetes mellitus.