CXCL1 and type 2 diabetes mellitus: Also, there is limited information about absolute levels in skeletal muscle or adipose tissue, especially in humans, although it has been reported that isolated macrophages and pre-adipocytes differentiated from human OAT secrete GRO and that such secretion is elevated several-fold in cells from obese individuals or with exposure to inflammatory agents [45], thereby supporting the supposition that T2D AT may be exposed in vivo to elevated levels of GROα.