Dysregulation of MAN1A1 has been shown to be associated with the tumor progression in various types of cancers including breast cancer, ovarian cancer, cholangiocarcinoma, and liver cancer (Legler et al., 2018; Phoomak et al., 2018; Hamester et al., 2019; Park et al., 2020). The gene discussed is MAN1A1; the disease is liver cancer.