NFE2L2 and cancer: For instance, the transcription factor nuclear factor erythroid 2-related factor 2 (NFE2L2), commonly referred to as Nrf2, is implicated in EMT regulation (Riahi et al., 2014) and is associated with poor clinical outcomes in cancer patients (Rojo de la Vega et al., 2018; Taguchi and Yamamoto, 2020).