Minoxidil is one of the few hair loss drugs approved by the FDA and was initially developed as a treatment for high blood pressure.1–4 Minoxidil induces peripheral vasodilation and increases blood flow by stimulating vascular endothelial growth factor (VEGF) expression.5–8 The efficacy of minoxidil varies depending on the individual, and when its use is discontinued, its hair-growth effect does not last, and eventually, hair loss recurs. Here, VEGFA is linked to hypertensive disorder.