PTEN and cancer: In concordance with previous studies miR-21 has been found to be overexpressed in various cancers like acute myeloid leukemia and multiple myeloma.19 Studies also have shown that miR-21 may involve modulating PTEN tumor suppressor gene that leads to hepatocellular carcinoma.20 Thus, the dysregulation of these miRNAs may be more likely to be the indicators of future carcinomas in individuals exposed to TNT.