The number of positive lymph nodes was in the range of 1-17; 90.4% (19 patients) of cases had progesterone and estrogen receptors positive cancer, 81% of patients underwent mastectomy, all patients received chemotherapy, 16 patients (76.2%) received radiation therapy, 19 patients (90.5%) of participants received adjuvant hormonal therapy and trastuzumab was given to 10 patients (47.6%), lung was the representative site of metastasis (54.5%) (Table 2). Here, ESR1 is linked to cancer.