Sakai et al. showed TGF-b1 signaling-a prominent epithelial mesenchymal transition associated factor-induced the motility of NSCLC A549 cells and that COL1A1 and COL3A1 were overexpressed in parallel with active TGF β signaling (Sakai et al., 2015). This evidence concerns the gene TGFB1 and non-small cell lung carcinoma.