Basic haematology, kidney function, ionogram, liver function, C-reactive protein, TSHANA, ANCA, RF, erythrocyte sedimentation rate, complement, lupus anticoagulants, anti-cardiolipin antibodies, serum electrophoresis, ACE, sedimentation, anti-AQP4 antibodies, anti-MOG antibodies, HIV, HBV, HCV, toxoplasma serology, CMV serology, VZV serology, EBV serology, syphilis serology, Borrelia serology, tumour markers, JCV titre, IGRA testNeurofilament light protein. The gene discussed is MOG; the disease is syphilis.