Mycoplasma infection functions as a p53-suppressing oncogene that collaborates with Ras in cell transformation, implying that mycoplasma’s carcinogenic and mutagenic effects are due to its inhibition of p53 tumor suppressor activity (367), which has been demonstrated in several Mycoplasma strains, ultimately resulting in downregulation of apoptosis of the damaged cells. This evidence concerns the gene TP53 and Mycoplasmoides infection.