CDK6 and adrenal cortex carcinoma: In general, CDK6 participates in the protection of cell genome stability and prevents cell mutations, which could lead to tumorigenesis (20) and similar results were found in the present study: T. hemsleyanum specifically inhibits the expression levels of CDK6, making it easy to cause genomic damage and to kill tumor cells, especially adrenocortical carcinoma, cervical cancer, low grade gliomas, and pancreatic cancer.