SERPINB3 and neoplasm: Preoperative squamous cell carcinoma antigen (SCCA) levels of ≥2.55 ng/mL, bulky tumor size of ≥4 cm, DSI greater than 1/2 thickness, positive LVSI, and parametrial invasion were observed in 62.0% (n = 240), 56.8% (n = 268), 85.8% (n = 400), 63.0% (n = 289), and 14.4% (n = 64) of the patients, respectively.