The results showed that 25 genes were significantly associated with the overall survival of Wilms tumor, namely ADRA2A, BCL6, CA10, CCNA1, CTHRC1, DGKD, EPB41L4B, ERRFI1, GALNT3, JAM2, LRRC40, MTF2, NCEH1 NEBL, OSBPL3, PDS5B, PDSS1, RFX3, ROR1, RTKN2, SLAIN1, SPTLC3, TICAM1, TUBGCP3, and ZFP36L2 (see Table 1). The gene discussed is PDS5B; the disease is Nephroblastoma.