The results showed that the C1 subtype was mainly enriched in some stromal and oncogenic activation pathways, such as TGF-β signaling pathway, ECM-receptor interaction, and basal cell carcinoma; the C2 subtype was mainly enriched in metabolic and repair-related pathways, such as glyoxylate and dicarboxylate metabolism, mismatch repair, and base excision repair. This evidence concerns the gene TGFB1 and basal cell carcinoma.