As demonstrated in Table 7, spontaneous pneumothorax (168), mutation (159), renal cell carcinoma (119), family (83), folliculin (83), BHD gene (68), cancer (66), fibrofolliculoma (66), pulmonary cyst (40), diagnosis (39), management (36), and tumor suppressor gene (33) were keywords with high occurrence frequency. Here, FLCN is linked to pneumothorax.