TJP1 and digestive system disorder: Taking together with the results regarding microbiota and intestinal epithelium, our results here suggest that cocoa consumption can improve intestinal health, especially by means of increasing cecal SCFA production and ZO1 expression, which could be useful not only to prevent the alterations induced by intensive exercise, but also in situations with an even more impaired intestinal barrier function, like some gastrointestinal disorders.