Besides, maternal HF also dramatically elevated the fasting glucose (p < 0.01), fasting insulin (p < 0.05), and HOMA-IR (p < 0.01), whereas maternal betaine played a role in reducing the level of fasting glucose (p < 0.05), fasting insulin (p < 0.01), and HOMA-IR (p < 0.01) compared to the HF group (Figures 3E–G). The gene discussed is INS; the disease is hydrops fetalis.