For example, STAT3 belonged to “regulation of apoptotic process,” “positive regulation of cell migration,” and “HIF-1 signaling pathway.” AKT1 was involved in many biological processes and pathways such as “negative regulation of apoptotic process,” “proliferation of smooth muscle cell,” “response to hypoxia,” and “HIF-1 signaling pathway.” The above results indicate that DSY can exert an anti-HPH effect through multiple targets and pathways, so DSY might be suitable for the complex mechanism of pulmonary hypertension. Here, STAT3 is linked to pulmonary arterial hypertension.