In addition, the exosomal CD31 and PFN2 levels in the MI group were significantly higher than those in the CTL group (p = 0.035/p = 0.025) (Figures 1D,E), which suggested that elevated PFN2 content might be associated with endothelial cells derived exosomes increasing in MI patients serum. The gene discussed is PFN2; the disease is myocardial infarction.